HPLC SEPARATION GUIDE March 2006 - Standard C18 column in high throughput LC-MS applications

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Introduction

In today's paradigm of drug discovery, high throughput screening of hit-to-lead compounds is commonplace. Researchers screen millions of chemical compounds found in commercially available and proprietary libraries in search of a lead molecule, which reacts in a pre-defined.

HPLC SEPARATION GUIDE JANUARY '96 - Analysis of Active Ingredients in a Sun Screen

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Introduction

The main purpose of sun-screening preparations is to protect human skin from the damaging effects of light. By far the best-known light-induced skin damage is light erythema, sunburn. It is caused by ultraviolet B (280-315nm) rays.

HPLC SEPARATION GUIDE April '96 - Analysis of Antibacterial Residues in Cow Milk

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Introduction

Flavonoids occur naturally in plant foods and are a common component of our diet. Flavonoids have demonstrated a wide range of biochemical and pharmacological effects, including antiinflammatory and antiallergic effects.

HPLC SEPARATION GUIDE March '97 - Low Detectability of Cocaine and Nicotine with SMT-QuickSep Column

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Introduction

The development of better analytical methods have always been the key to effective detectability of low concentration of organic compounds. Ability to detect and isolate low concentration of analytes is not only crucial.

HPLC SEPARATION GUIDE JULY '96- Separation of the Gentamicin Complex

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Introduction

The antibiotic gentamicin complex consists of at least four closely related isomeric pseudo-oligosaccharides referred to as gentamicin C1, C1a, C2 and C2a (see Figure 1).