SMT-Diol column is developed as an alternative for silica column used in normal phase separation methods. The Diol [-OH] functional group is controlled, and as such, provides more reproducible separation when compared to separation on silanols [-OH] from bare silica surface. Furthermore, the hydrogen bonding on the OH functional group on Diol packing material is not as strong as that of bare silica. This results in a reduced interaction of polar compounds on the column. SMT-Diol can be used in normal and reversed-phase separation of pesticides, herbicides, pharmaceutical metabolites, polar natural products, proteins, peptides and other polar biomolecules.
High loading capability and improved sample recovery
High reproducibility of bonded ligand resulting in consistent separation.
Increased longevity provided through “total coverage”.
SMT offers two types of Diol columns:
SMT-Diol1 columns-consist of acid-catalyzed cleavage of 3-(2,3-epoxypropoxy) propyl as the functional ligand SMT-Diol2 columns-consist of acid-catalyzed cleavage of 5,6-epoxyhexyl as the functional ligand. Just like the silica substrate, both of these packings can be subjected to further treatment or modification with another functional ligand for special applications.
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