SMT-Diol column is developed as an alternative for silica column used in normal phase separation methods. The Diol [-OH] functional group is controlled, and as such, provides more reproducible separation when compared to separation on silanols [-OH] from bare silica surface. Furthermore, the hydrogen bonding on the OH functional group on Diol packing material is not as strong as that of bare silica. This results in a reduced interaction of polar compounds on the column. SMT-Diol can be used in normal and reversed-phase separation of pesticides, herbicides, pharmaceutical metabolites, polar natural products, proteins, peptides and other polar biomolecules.
Unique features:
High loading capability and improved sample recovery
High reproducibility of bonded ligand resulting in consistent separation.
Increased longevity provided through “total coverage”.
SMT offers two types of Diol columns:
SMT-Diol1 columns-consist of acid-catalyzed cleavage of 3-(2,3-epoxypropoxy) propyl as the functional ligand SMT-Diol2 columns-consist of acid-catalyzed cleavage of 5,6-epoxyhexyl as the functional ligand. Just like the silica substrate, both of these packings can be subjected to further treatment or modification with another functional ligand for special applications.
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