Referenced Articles

 
  • Erathodiyil Nandanan, Emidio Camaioni, Soo-Yeon Jang, Yong-Chul Kim, Gloria Cristalli, Piet Herdewijn, John A. Secrist, III, Kamal N. Tiwari, Arvind Mohanram, T. Kendall Harden, José L. Boyer, and Kenneth A. Jacobson J. Med. Chem., 1999, 42 (9), pp 1625–1638
    Publication Date (Web): April 21, 1999 (Article) DOI: 10.1021/jm980657j Purity of compounds was checked by a Hewlett-Packard 1090 HPLC apparatus using SMT OD-5-60 RP-C18 (250 × 4.6 mm; Separation Methods Technologies, Inc., Newark, DE) as an analytical column in two solvent systems. ... The reaction was monitored by analytical HPLC (eluting with gradient from buffer, CH3CN = 95:5 to 40:60; buffer, 0.1 M triethylammonium acetate (TEAA); elution time, 20 min; flow rate, 1 mL/min; column, SMT OD-5-60 RP-C18; detector, UV, Emax 260−300 nm). ... a Purity of each derivative was 95%, as determined using HPLC (Hewlett-Packard 1090) with two different mobile phases, using an SMT OD-5-60 RP-C18 column (250 × 4.6 mm; Separation Methods Technologies, Inc., Newark, DE)...
     
  • Emidio Camaioni, José L. Boyer, Arvind Mohanram, T. Kendall Harden, and Kenneth A. Jacobson J. Med. Chem., 1998, 41 (2), pp 183–190 Publication Date (Web): January 15, 1998 (Article) DOI: 10.1021/jm970433l
    Purity of compounds was checked by a Hewlett-Packard 1090 HPLC apparatus using SMT OD-5-60 RP-C18 (250 × 4.6 mm; Separation Methods Technologies, Inc., Newark, DE) as an analytical column in two- solvent systems. ... The reaction was monitored by analytical HPLC (eluting with gradient from buffer:CH3CN = 95:5 to 40:60; buffer, 0.1 M triethylammonium acetate (TEAA); elution time, 20 min; flow rate, 1 mL/min; column, SMT OD-5-60 RP-C18; detector, UV, Emax ≈ 260−300 nm)...
     
  • Yong-Chul Kim, Xiao-duo Ji, and Kenneth A. Jacobson J. Med. Chem., 1996, 39 (21), pp 4142–4148 Publication Date (Web): October 11, 1996 (Expedited Article) DOI: 10.1021/jm960482i
    Where needed evaluation of purity was done on a Hewlett-Packard 1090 HPLC system using OD-5-60 C18 analytical column (150 mm × 4.6 mm, Separation Methods Technologies, Inc., Newark, DE) in two different linear gradient solvent systems...
     
  • Kenneth A. Jacobson, Yong-Chul Kim, Scott S. Wildman, Arvind Mohanram, T. Kendall Harden, José L. Boyer, Brian F. King, and Geoffrey Burnstock J. Med. Chem., 1998, 41 (13), pp 2201–2206 Publication Date (Web): June 03, 1998 (Expedited Article)
    DOI: 10.1021/jm980183o Determination of purity were performed with a Hewlett-Packard 1090 HPLC system using an OD-5-60 C18 analytical column (250 mm × 4.6 mm, Separation Methods Technologies, Inc., Newark, DE) in two different linear gradient solvent systems...
     
  • Erathodiyil Nandanan, Soo-Yeon Jang, Stefano Moro, Hea Ok Kim, Maqbool A. Siddiqui, Pamela Russ, Victor E. Marquez, Roger Busson, Piet Herdewijn, T. Kendall Harden, José L. Boyer, and Kenneth A. Jacobson J. Med. Chem., 2000, 43 (5), pp 829–842
    Publication Date (Web): February 23, 2000 (Article) DOI: 10.1021/jm990249v Purity of compounds was checked using a Hewlett-Packard 1090 HPLC apparatus equipped with an SMT OD-5-60 RP-C18 analytical column (250 × 4.6 mm; Separation Methods Technologies, Inc., Newark, DE) in two solvent systems. ... The reaction was monitored by analytical HPLC (eluting with a gradient consisting of buffer:CH3CN in the ratio 95:5 to 40:60, in which the buffer was 0.1 M triethylammonium acetate (TEAA); elution time was 20 min; flow rate was 1 mL/min; column was SMT OD-5-60 RP-C18; detector was by UV in the Emax range of 260−300 nm)...
     
  • Yong-Chul Kim, Maarten de Zwart, Louis Chang, Stefano Moro, Jacobien K. von Frijtag Drabbe Künzel, Neli Melman, Ad P. IJzerman, and Kenneth A. Jacobson J. Med. Chem., 1998, 41 (15), pp 2835–2845 Publication Date (Web): June 18, 1998 (Article) DOI: 10.1021/jm980094b
    Where needed, evaluation of purity was done on a Hewlett-Packard 1090 HPLC system using an OD-5- 60 C18 analytical column (150 mm × 4.6 mm; Separation Methods Technologies, Inc., Newark, DE) in two different linear gradient solvent systems...
     
  • Ji-long Jiang, An-Hu Li, Soo-Yeon Jang, Louis Chang, Neli Melman, Stefano Moro, Xiao-duo Ji, Emil B. Lobkovsky, Jon C. Clardy, and Kenneth A. Jacobson J. Med. Chem., 1999, 42 (16), pp 3055–3065 Publication Date (Web): July 22, 1999 (Article) DOI: 10.1021/jm980688e
    Purity of diastereomers 9−12 and enantiomers of MRS 1191, compounds 21 (4S)and 23 (4R), was checked by HPLC using SMT OD-5-60 RP C18 (250 × 4.6 mm) as an analytical column in two solvent systems...
     
  • Yong-Chul Kim, Sean G. Brown, T. Kendall Harden, José L. Boyer, George Dubyak, Brian F. King, Geoffrey Burnstock, and Kenneth A. Jacobson J. Med. Chem., 2001, 44 (3), pp 340–349 Publication Date (Web): December 19, 2000 (Article) DOI: 10.1021/jm9904203
    The determinations of purity were performed with a Hewlett-Packard 1090 HPLC system using an OD-5- 60 C18 analytical column (250 mm × 4.6 mm; Separation Methods Technologies, Inc., Newark, DE) in two different linear gradient solvent systems...
     
  • Hak Sung Kim, R. Gnana Ravi, Victor E. Marquez, Savitri Maddileti, Anna-Karin Wihlborg, David Erlinge, Malin Malmsjö, José L. Boyer, T. Kendall Harden, and Kenneth A. Jacobson J. Med. Chem., 2002, 45 (1), pp 208–218 Publication Date (Web): November 22, 2001 (Article) DOI: 10.1021/jm010369e
    Purity of all compounds in solvent 1 and compounds 5a, 6a, and 7a in solvent 2 was checked using an SMT OD-5-60 RP-C18 analytical column (250 × 4.6 mm; Separation Methods Technologies, Inc., Newark, DE) in two solvent systems...
     
  • Kenneth A. Jacobson, Xiao-duo Ji, An-Hu Li, Neli Melman, Maqbool A. Siddiqui, Kye-Jung Shin, Victor E. Marquez, and R. Gnana Ravi J. Med. Chem., 2000, 43 (11), pp 2196–2203 Publication Date (Web): May 16, 2000 (Article)
    DOI: 10.1021/jm9905965 The determination of purity was performed with a Hewlett-Packard 1090 HPLC system using an SMT OD-5- 60 C18 analytical column (250 mm × 4.6 mm, Separation Methods Technologies, Inc., Newark, DE) in two different linear gradient solvent systems...
     
  • Yong-Chul Kim, Xiao-duo Ji, Neli Melman, Joel Linden, and Kenneth A. Jacobson J. Med. Chem., 2000, 43 (6), pp 1165–1172 Publication Date (Web): February 26, 2000 (Article) DOI: 10.1021/jm990421v
    Where needed, evaluation of purity was done on a Hewlett-Packard 1090 HPLC system using an OD-5- 60 C18 analytical column (150 mm × 4.6 mm; Separation Methods Technologies, Inc., Newark, DE) in two different linear gradient solvent systems, at a flow rate of 1 mL/min...
     
  • Yong-Chul Kim, Carola Gallo-Rodriguez, Soo-Yeon Jang, Erathodiyil Nandanan, Mary Adams, T. Kendall Harden, José L. Boyer, and Kenneth A. Jacobson J. Med. Chem., 2000, 43 (4), pp 746–755 Publication Date (Web): February 09, 2000 (Article) DOI: 10.1021/jm9905211
    The determinations of purity were performed with a Hewlett-Packard 1090 HPLC system using an SMT OD- 5-60 C18 analytical column (250 mm × 4.6 mm, Separation Methods Technologies, Inc., Newark, DE) in two different linear gradient solvent systems...
     
  • R. Gnana Ravi, Hak Sung Kim, Jörg Servos, Herbert Zimmermann, Kyeong Lee, Savitri Maddileti, José L. Boyer, T. Kendall Harden, and Kenneth A. Jacobson J. Med. Chem., 2002, 45 (10), pp 2090–2100 Publication Date (Web): April 12, 2002 (Article) DOI: 10.1021/jm010538v
    Purity of compounds was checked using a Hewlett-Packard 1090 HPLC apparatus equipped with an SMT OD-5-60 RP-C18 analytical column (250 mm × 4.6 mm; Separation Methods Technologies, Inc., Newark, DE) in two solvent systems...
     
  • Hak Sung Kim, Dov Barak, T. Kendall Harden, José L. Boyer, and Kenneth A. Jacobson J. Med. Chem., 2001, 44 (19), pp 3092–3108 Publication Date (Web): August 22, 2001 (Article) DOI: 10.1021/jm010082h
    The determinations of purity were performed with a Hewlett-Packard 1090 HPLC system using an SMT OD- 5-60 C18 analytical column (250 mm × 4.6 mm, Separation Methods Technologies, Inc., Newark, DE) in two different linear gradient solvent systems...
     
  • Erathodiyil Nandanan, Emidio Camaioni, Soo-Yeon Jang, Yong-Chul Kim, Gloria Cristalli, Piet Herdewijn, John A. Secrist, III, Kamal N. Tiwari, Arvind Mohanram, T. Kendall Harden, José L. Boyer, and Kenneth A. Jacobson J. Med. Chem., 1999, 42 (9), pp 1625–1638
    Publication Date (Web): April 21, 1999 (Article)
    DOI: 10.1021/jm980657j
    Purity of compounds was checked by a Hewlett-Packard 1090 HPLC apparatus using SMT OD-5-60 RP-C18 (250 × 4.6 mm; Separation Methods Technologies, Inc., Newark, DE) as an analytical column in two solvent systems. ... The reaction was monitored by analytical HPLC (eluting with gradient from buffer, CH3CN = 95:5 to 40:60; buffer, 0.1 M triethylammonium acetate (TEAA); elution time, 20 min; flow rate, 1 mL/min; column, SMT OD-5-60 RP-C18; detector, UV, Emax 260−300 nm). ... a Purity of each derivative was 95%, as determined using HPLC (Hewlett-Packard 1090) with two different mobile phases, using an SMT OD-5-60 RP-C18 column (250 × 4.6 mm; Separation Methods Technologies, Inc., Newark, DE)...
     
  • Derivatives of the Triazoloquinazoline Adenosine Antagonist (CGS15943) Are Selective for the Human A3Receptor Subtype
    Yong-Chul Kim, Xiao-duo Ji, and Kenneth A. Jacobson J. Med. Chem., 1996, 39 (21), pp 4142–4148 Publication Date (Web): October 11, 1996 (Expedited Article) DOI: 10.1021/jm960482i
    Where needed evaluation of purity was done on a Hewlett-Packard 1090 HPLC system using OD-5-60 C18 analytical column (150 mm × 4.6 mm, Separation Methods Technologies, Inc., Newark, DE) in two different linear gradient solvent systems...
     
  • Deoxyadenosine Bisphosphate Derivatives as Potent Antagonists at P2Y1 Receptors
    Emidio Camaioni, José L. Boyer, Arvind Mohanram, T. Kendall Harden, and Kenneth A. Jacobson J. Med. Chem., 1998, 41 (2), pp 183–190 Publication Date (Web): January 15, 1998 (Article) DOI: 10.1021/jm970433l
    Purity of compounds was checked by a Hewlett-Packard 1090 HPLC apparatus using SMT OD-5-60 RP-C18 (250 × 4.6 mm; Separation Methods Technologies, Inc., Newark, DE) as an analytical column in two-solvent systems. ... The reaction was monitored by analytical HPLC (eluting with gradient from buffer:CH3CN = 95:5 to 40:60; buffer, 0.1 M triethylammonium acetate (TEAA); elution time, 20 min; flow rate, 1 mL/min; column, SMT OD-5-60 RP-C18; detector, UV, Emax ≈ 260−300 nm)...
     
  • Structure−Activity Relationships of Bisphosphate Nucleotide Derivatives as P2Y1 Receptor Antagonists
    and Partial Agonists
    Erathodiyil Nandanan, Emidio Camaioni, Soo-Yeon Jang, Yong-Chul Kim, Gloria Cristalli, Piet Herdewijn, John A. Secrist, III, Kamal N. Tiwari, Arvind Mohanram, T. Kendall Harden, José L. Boyer, and Kenneth A. Jacobson J. Med. Chem., 1999, 42 (9), pp 1625–1638 Publication Date (Web): April 21, 1999 (Article)
    DOI: 10.1021/jm980657j Purity of compounds was checked by a Hewlett-Packard 1090 HPLC apparatus using SMT OD-5-60 RP-C18 (250 × 4.6 mm; Separation Methods Technologies, Inc., Newark, DE) as an analytical column in two solvent systems. ... The reaction was monitored by analytical HPLC (eluting with gradient from buffer, CH3CN = 95:5 to 40:60; buffer, 0.1 M triethylammonium acetate (TEAA); elution time, 20 min; flow rate, 1 mL/min; column, SMT OD-5-60 RP-C18; detector, UV, Emax 260−300 nm). ... a Purity of each derivative was 95%, as determined using HPLC (Hewlett-Packard 1090) with two different mobile phases, using an SMT OD-5-60 RP-C18 column (250 × 4.6 mm; Separation Methods Technologies, Inc., Newark, DE)...
     
  • Chiral Resolution and Stereospecificity of 6-Phenyl-4-phenylethynyl- 1,4-dihydropyridines as Selective A3Adenosine Receptor Antagonists
    Ji-long Jiang, An-Hu Li, Soo-Yeon Jang, Louis Chang, Neli Melman, Stefano Moro, Xiao-duo Ji, Emil B. Lobkovsky, Jon C. Clardy, and Kenneth A. Jacobson J. Med. Chem., 1999, 42 (16), pp 3055–3065 Publication Date (Web): July 22, 1999 (Article)
    DOI: 10.1021/jm980688e
    The essential modifications leading to A3 selectivity and preventing binding to L-type calcium channels and other sites are a phenyl ring at the 6-position and at the 4-position either a styryl or a phenylethynyl group (e.g. 1 and 2, Figure 1). ... Purity of diastereomers 9−12 and enantiomers of MRS 1191, compounds 21 (4S)and 23 (4R), was checked by HPLC using SMT OD-5-60 RP C18 (250 × 4.6 mm) as an analytical column in two solvent systems.
    After cooling to room temperature, the solvent was removed under reduced pressure, and the residue was purified by column chromatography (silica 60; CH2Cl2) to give 0.932 g of compound 5, yield: 54%. 1H NMR: δ 1.37 (s, 3 H), 1.44 (s, 3 H), 2.29 (s, 3 H), 3.77 (m, 1 H), 4.07 (m, 1 H), 3.52 (s, 2 H), 4.22 (m, 2 H), 4.35 (m, 1 H). Purity of diastereomers 9−12 and enantiomers of MRS 1191, compounds 21 (4S) and 23 (4R), was checked by HPLC using SMT OD-5-60 RP C18(250 × 4.6 mm) as an analytical column in two solvent systems. Purity of diastereomers 9−12 and enantiomers of MRS 1191, compounds 21 (4S)and 23 (4R), was checked by HPLC using SMT OD-5-60 RP C18 (250 × 4.6 mm) as an analytical column in two solvent systems.
     
  • Acyclic Analogues of Deoxyadenosine 3',5'-Bisphosphates as P2Y1 Receptor Antagonists
    Yong-Chul Kim, Carola Gallo-Rodriguez, Soo-Yeon Jang, Erathodiyil Nandanan, Mary Adams, T. Kendall Harden, José L. Boyer, and Kenneth A. Jacobson J. Med. Chem., 2000, 43 (4), pp 746–755 Publication Date (Web): February 09, 2000 (Article)
    DOI: 10.1021/jm9905211 The determinations of purity were performed with a Hewlett-Packard 1090 HPLC system using an SMT OD-5- 60 C18 analytical column (250 mm × 4.6 mm, Separation Methods Technologies, Inc., Newark, DE) in two different linear gradient solvent systems. ... The residue was purified with an ion-exchangecolumn chromatography using Sephadex-DEAE A-25 resin with a linear gradient (0.01 to 0.5 M) of 0.5 M ammonium bicarbonate as the mobile phase to give 18 mg of 8 (88%)...
     
  • Synthesis, Biological Activity, and Molecular Modeling of Ribose-Modified Deoxyadenosine Bisphosphate Analogues as P2Y1 Receptor Ligands
    Erathodiyil Nandanan, Soo-Yeon Jang, Stefano Moro, Hea Ok Kim, Maqbool A. Siddiqui, Pamela Russ, Victor E. Marquez, Roger Busson, Piet Herdewijn, T. Kendall Harden, José L. Boyer, and Kenneth A. Jacobson J. Med. Chem., 2000, 43 (5), pp 829–842 Publication Date (Web): February 23, 2000 (Article)
    DOI: 10.1021/jm990249v Purity of compounds was checked using a Hewlett-Packard 1090 HPLC apparatus equipped with an SMT OD-5-60 RP-C18 analytical column (250 × 4.6 mm; Separation Methods Technologies, Inc., Newark, DE) in two solvent systems. ... However, compounds 7b and 8a−c required HPLC purification (system A, semipreparative C18 column) of the reaction mixtures...
     
  • Anilide Derivatives of an 8-Phenylxanthine Carboxylic Congener Are Highly Potent and Selective Antagonists at Human A2B Adenosine Receptors
    Yong-Chul Kim, Xiao-duo Ji, Neli Melman, Joel Linden, and Kenneth A. Jacobson J. Med. Chem., 2000, 43 (6), pp 1165–1172 Publication Date (Web): February 26, 2000 (Article) DOI: 10.1021/jm990421v
    Where needed, evaluation of purity was done on a Hewlett-Packard 1090 HPLC system using an OD-5-60 C18 analytical column (150 mm × 4.6 mm; Separation Methods Technologies, Inc., Newark, DE) in two different linear gradient solvent systems, at a flow rate of 1 mL/min...
     
  • Methanocarba Analogues of Purine Nucleosides as Potent and Selective Adenosine Receptor Agonists
    Kenneth A. Jacobson, Xiao-duo Ji, An-Hu Li, Neli Melman, Maqbool A. Siddiqui, Kye-Jung Shin, Victor E. Marquez, and R. Gnana Ravi J. Med. Chem., 2000, 43 (11), pp 2196–2203 Publication Date (Web): May 16, 2000 (Article)
    DOI: 10.1021/jm9905965 The determination of purity was performed with a Hewlett-Packard 1090 HPLC system using an SMT OD-5- 60 C18 analytical column (250 mm × 4.6 mm, Separation Methods Technologies, Inc., Newark, DE) in two different linear gradient solvent systems. ... Solvent was removed under vacuum, and the residue obtained was purified by flash column chromatography using 7/3 chloroform/methanol to furnish 3.0 mg (47%) of the product, mp. 85 °C...
     
  • Structure−Activity Relationships of Pyridoxal Phosphate Derivatives as Potent and Selective Antagonists of P2X1Receptors
    Yong-Chul Kim, Sean G. Brown, T. Kendall Harden, José L. Boyer, George Dubyak, Brian F. King, Geoffrey Burnstock, and Kenneth A. Jacobson J. Med. Chem., 2001, 44 (3), pp 340–349 Publication Date (Web): December 19, 2000 (Article)
    DOI: 10.1021/jm9904203 The determinations of purity were performed with a Hewlett-Packard 1090 HPLC system using an OD-5-60 C18 analytical column (250 mm × 4.6 mm; Separation Methods Technologies, Inc., Newark, DE) in two different linear gradient solvent systems...
     
  • Acyclic and Cyclopropyl Analogues of Adenosine Bisphosphate Antagonists of the P2Y1 Receptor:
    Structure−Activity Relationships and Receptor Docking
    Hak Sung Kim, Dov Barak, T. Kendall Harden, José L. Boyer, and Kenneth A. Jacobson J. Med. Chem., 2001, 44 (19), pp 3092–3108 Publication Date (Web): August 22, 2001 (Article) DOI: 10.1021/jm010082h
    The determinations of purity were performed with a Hewlett-Packard 1090 HPLC system using an SMT OD-5-60 C18 analytical column (250 mm × 4.6 mm, Separation Methods Technologies, Inc., Newark, DE) in two different linear gradient solvent systems. ... After removal of volatile materials in vacuo, the residue was purified by column chromatography (ethyl acetate/methanol = 10:1) to give diol 77 (275 mg, 95%)...
     
  • Methanocarba Modification of Uracil and Adenine Nucleotides: High Potency of Northern Ring Conformation at P2Y1, P2Y2, P2Y4, and P2Y11 but Not P2Y6 Receptors
    Hak Sung Kim, R. Gnana Ravi, Victor E. Marquez, Savitri Maddileti, Anna-Karin Wihlborg, David Erlinge, Malin Malmsjö, José L. Boyer, T. Kendall Harden, and Kenneth A. Jacobson J. Med. Chem., 2002, 45 (1), pp 208–218 Publication Date (Web): November 22, 2001 (Article)
    DOI: 10.1021/jm010369e Purity of all compounds in solvent 1 and compounds 5a, 6a, and 7a in solvent 2 was checked using an SMT OD-5-60 RP-C18 analytical column ... Compounds 3a, 4a,8a, and 9a were checked in solvent 2 using a Phenomenex Luna 5μ C18(2) analytical column (250 × 4.6 mm). ...
    Purity of all compounds in solvent 1 and compounds 5a, 6a, and 7a in solvent 2 was checked using an SMT OD-5-60 RP-C18 analytical column (250 × 4.6 mm; Separation Methods Technologies, Inc., Newark, DE) in two solvent systems. ...(1'S,2'R,3'S,4'R,5'S)-4-(6-Amino-9H-purin-9-yl)-1-[phosphoryloxymethyl]bicyclo[3.1.0]hexane-2,3-diol (4a)...
     
  • Adenine Nucleotide Analogues Locked in a Northern Methanocarba Conformation: Enhanced Stability and Potency as P2Y1 Receptor Agonists R. Gnana Ravi, Hak Sung Kim, Jörg Servos, Herbert Zimmermann, Kyeong Lee, Savitri Maddileti, José L. Boyer, T. Kendall Harden, and Kenneth A. Jacobson J. Med. Chem., 2002, 45 (10), pp 2090–2100 Publication Date (Web): April 12, 2002 (Article) DOI: 10.1021/jm010538v
    Purity of compounds was checked using a Hewlett-Packard 1090 HPLC apparatus equipped with an SMT OD-5-60 RP-C18 analytical column (250 mm × 4.6 mm; Separation Methods Technologies, Inc., Newark, DE) in two solvent systems. ... (1'S,2'R,3'S,4'R,5'S)-4-(6-Amino-9H-purin-9-yl)-1-[(phenyl methoxy)methyl]bicyclo[3.1.0 ]hexane-2,3-(O-isopropyl-idene) (23)...
     
  • Structure−Activity Relationships at Human and Rat A2BAdenosine Receptors of Xanthine Derivatives
    Substituted at the 1-, 3-, 7-, and 8-Positions
    Soon-Ai Kim, Melissa A. Marshall, Neli Melman, Hak Sung Kim, Christa E. Müller, Joel Linden, and Kenneth A. Jacobson J. Med. Chem., 2002, 45 (11), pp 2131–2138 Publication Date (Web): April 25, 2002 (Article) DOI: 10.1021/jm0104318
    Phenyl ring-substituted analogues of 49 were also tested: The electron-withdrawing 2,6-difluoro and 4-chloro groups on the 8- aromatic ring, in 53 and60, reduced affinity. ... Where needed, determinations of purity were performed with a Hewlett- Packard 1090 high-performance liquid chromatography (HPLC) system using an SMT OD-5−60 C18 analytical column (250 mm × 4.6 mm, Separation Methods Technologies, Inc., Newark, DE) in two different linear gradient solvent systems...
     
  • Derivatives of the Triazoloquinazoline Adenosine Antagonist (CGS15943) Are Selective for the Human A3Receptor Subtype
    Yong-Chul Kim, Xiao-duo Ji, and Kenneth A. Jacobson J. Med. Chem., 1996, 39 (21), pp 4142–4148 Publication Date (Web): October 11, 1996 (Expedited Article) DOI: 10.1021/jm960482i
    Where needed evaluation of purity was done on a Hewlett-Packard 1090 HPLC system using OD-5-60 C18 analytical column (150 mm × 4.6 mm, Separation Methods Technologies, Inc., Newark, DE) in two different linear gradient solvent systems...
     
  • A Pyridoxine Cyclic Phosphate and Its 6-Azoaryl Derivative Selectively Potentiate and Antagonize Activation of P2X1Receptors
    Kenneth A. Jacobson, Yong-Chul Kim, Scott S. Wildman, Arvind Mohanram, T. Kendall Harden, José L. Boyer, Brian F. King, and Geoffrey Burnstock J. Med. Chem., 1998, 41 (13), pp 2201–2206 Publication Date (Web): June 03, 1998 (Expedited Article)
    DOI: 10.1021/jm980183o Determination of purity were performed with a Hewlett-Packard 1090 HPLC system using an OD-5-60 C18 analytical column (250 mm × 4.6 mm, Separation Methods Technologies, Inc., Newark, DE) in two different linear gradient solvent systems...
     
  • Synthesis, Biological Activity, and Molecular Modeling of Ribose-Modified Deoxyadenosine Bisphosphate Analogues as P2Y1 Receptor Ligands
    Erathodiyil Nandanan, Soo-Yeon Jang, Stefano Moro, Hea Ok Kim, Maqbool A. Siddiqui, Pamela Russ, Victor E. Marquez, Roger Busson, Piet Herdewijn, T. Kendall Harden, José L. Boyer, and Kenneth A. Jacobson J. Med. Chem., 2000, 43 (5), pp 829–842 Publication Date (Web): February 23, 2000 (Article)
    DOI: 10.1021/jm990249v
    Purity of compounds was checked using a Hewlett-Packard 1090 HPLC apparatus equipped with an SMT OD-5-60 RP-C18 analytical column (250 × 4.6 mm; Separation Methods Technologies, Inc., Newark, DE) in two solvent systems. ... The reaction was monitored by analytical HPLC (eluting with a gradient consisting of buffer:CH3CN in the ratio 95:5 to 40:60, in which the buffer was 0.1 M triethylammonium acetate (TEAA); elution time was 20 min; flow rate was 1 mL/min; column was SMT OD-5- 60 RP-C18; detector was by UV in the Emax range of 260−300 nm).
     
  • Measurement of Food Flavonoids by High-Performance Liquid Chromatography: A Review
    Howard M. Merken and Gary R. Beecher J. Agric. Food Chem., 2000, 48 (3), pp 577–599 Publication Date (Web): February 29, 2000 (Review) DOI: 10.1021/jf990872o
    After HPLC, samples can be further purified for mass spectrometry (MS) usingcolumn chromatography, as was done for Zambian munkoyo beverage (Zulu et al., 1994). ... Zorbax Rx-C18 and SMT OD-5-100 columns also worked for system 1; Zorbax Rx-C18 worked for system 2.g Develosil ODS-HG-5 (10 × 4 mm).
     
  • Direct determination of phosphorilated intercellular anabolites of stavudine (d4T) by liquid chromatography/tandem mass spectrometry: RCM 2001, 15, 1401-1408.
     
  • Improved method for the simultaneous determination of d4T, 3TC and ddl intercellular phosphorylated anabolites in human peripheral-blood mononuclear cells using high-performance liquid chromatography/tandem mass spectrometry: RCM 2002, 16, 555-565.
     
  • Optical and Chromaticity Characteristics of Adsorbates of the Thorium Complex of Arsenazo I: Journal of Analytical Chemistry 2003, 58, 318-321.
     
  • Silica and other materials as supports in liquid chromatography, chromatographic tests and their importance for evaluating these supports, Part I: Chromatographia 2001, 53, S113-S131.
     
  • Determination of Aluminum and Beryllium by Diffuse Reflectance Spectrometry with the Use of Chromaticity Functions: Journal of Analytical Chemistry 2001, 56, 1089-1094.
     
  • Beta-Homolysine conjugates and their use as transport enhancer: European Patent EP1478405.
     
  • Organic compounds having Anti-angiogenic activity: European Patent EP1478665.
     
  • Sulfonamidomethyl phosphonate inhibitors of I2-lactamase: United States Patent 7030103 Issued on April 18, 2006.
     
  • Methanocarba cycloakyl nucleoside analogues: United States Patent 7087589 Issued on August 8, 2006.
     
  • RP-HPLC determination of the study of the material Balofloxacin: Unknown Source: Unknown Release time.
     
  • Arsenic Speciation in Human Organs following Fatal Arsenic Trioxide Poisoning – A Case Report: Clinical Chemistry 1999, 45, 301-306.
     
  • FeIII – TAML-catalyzed green oxidative degradation of the azo dye Orange II by H2O2 and organic peroxides: products, toxicity, kinetics, and mechanisms: Green Chemistry 2007, 9, 49-57.
     
  • Activity-Stability Parameterization of Homogeneous Green Oxidation Catalysts: Chemistry – A European Journal 2006, 12, 9336-9345.
     
  • Determination of Chromium(III) Picolinate Using High Performance Liquid Chromatography-Ultraviolet Spectrophotometry: Bull. Korean Chem. Soc. 2003, 24, 1517-1520.

 

 

 

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